Skip to content
Categories NFL

NFL Week 3 Expert Picks & Early Odds: Lions-Cardinals, Dolphins-Seahawks & More

Updated September 19, 2024 | 2:36 pm CDT by Isaiah Sirois

We’re on to Wednesday, so while we’ve got NFL action tomorrow, most of the slate will have to wait until the weekend. We do have two Monday Night Football games this week as well, with the Bills hosting the Jaguars and the Bengals hosting the Commanders. Let’s dive into the early NFL odds for Week 3 — as well as an NFL Week 3 expert pick. If you need more NFL betting strategy guide.

NFL Week 3 Expert Picks & Early Odds

React App

NFL Week 3 Expert Picks & Early Odds: Lions-Cardinals, Dolphis-Seahawks & More

What Have We Learned So Far?

Let’s take a quick look at the biggest year-over-year movers in offensive EPA (or EPA per play, so positive numbers indicate improvement), defensive EPA (or EPA per play allowed, so negative numbers indicate improvement) and net EPA (EPA per play – EPA per play allowed) through Week 2.

Team Δ Offensive EPA Δ Defensive EPA Δ Net EPA
New Orleans 0.322 -0.216 0.538 🔥
LA Chargers 0.093 -0.42 0.513 🔥
Arizona 0.25 -0.1 0.35
Minnesota 0.089 -0.196 0.285
Buffalo 0.122 -0.086 0.208
Pittsburgh -0.035 -0.216 0.181
Seattle -0.024 -0.198 0.174
New England 0.212 0.043 0.169
NY Jets 0.27 0.143 0.127
Washington 0.267 0.148 0.119
Houston 0.058 -0.06 0.118
Tampa Bay 0.158 0.043 0.115
Cincinnati -0.04 -0.06 0.02
Atlanta 0.025 0.022 0.003
Chicago -0.182 -0.185 0.003
Green Bay -0.021 -0.016 -0.005
Tennessee -0.138 -0.126 -0.012
Jacksonville -0.025 0.038 -0.063
Kansas City 0.034 0.11 -0.076
Indianapolis 0.006 0.097 -0.091
Philadelphia 0.004 0.104 -0.1
Detroit -0.059 0.043 -0.102
Las Vegas -0.1 0.012 -0.112
Cleveland -0.038 0.091 -0.129
Denver -0.231 -0.085 -0.146
NY Giants 0.031 0.184 -0.153
San Francisco -0.154 0.024 -0.178
Baltimore -0.055 0.18 -0.235
Miami -0.229 0.083 -0.312
LA Rams -0.102 0.234 -0.336
Dallas -0.254 0.091 -0.345
Carolina -0.32 0.126 -0.446 💩

Two games does not a representative sample make, but it’s worth noting just how much better a few teams look (New Orleans, LA Chargers, Arizona) and how much worse some others look (Carolina, Dallas, LA Rams, Miami). Make sure to adjust your priors accordingly.

React App

Early NFL Odds for Week 3

Let’s look at some of the NFL odds at BetMGM for Week 3’s full slate of games.

New England @ NY Jets
Spread: NY Jets -6.5
Total: O/U 38.5

Green Bay @ Tennessee
Spread: Tennessee -3
Total: O/U 36.5

Houston @ Minnesota
Spread: Houston -2.5
Total: O/U 46

LA Chargers @ Pittsburgh
Spread: Pittsburgh -1.5
Total: O/U 53.5

Carolina @ Las Vegas
Spread: Las Vegas -5.5
Total: O/U 41

Baltimore @ Dallas
Spread: Baltimore -1.5
Total: O/U 48.5

Detroit @ Arizona
Spread: Detroit -3
Total: O/U 52.5

Jacksonville @ Buffalo
Spread: Buffalo -5.5
Total: O/U 45.5

NY Giants @ Cleveland
Spread: Cleveland -6.5
Total: O/U 38.5

Chicago @ Indianapolis
Spread: Indianapolis -1
Total: O/U 43.5

Philadelphia @ New Orleans
Spread: New Orleans -2.5
Total: O/U 49.5

Denver @ Tampa Bay
Spread: Tampa Bay -7
Total: O/U 39.5

Miami @ Seattle
Spread: Seattle -4.5
Total: O/U 41.5

San Francisco @ LA Rams
Spread: San Francisco -7.5
Total: O/U 43.5

Kansas City @ Atlanta
Spread: Kansas City -3.5
Total: O/U 46.5

Washington @ Cincinnati
Spread: Cincinnati -7.5
Total: O/U 48.5

NFL Expert Pick for Week 3: Detroit Lions @ Arizona Cardinals

Check out our expert picks page for all of today’s free plays — or click here to sign up for Isaiah’s picks!

It’s hard to beat the NFL betting market. The two most improved teams on the above chart, the New Orleans Saints and Los Angeles Chargers, are priced quite fairly in Week 3. The Saints are now home favorites over the Eagles. The Chargers are now slim road dogs to the Pittsburgh Steelers, another much-improved team.

But then we get to the third-most-improved team, the Arizona Cardinals, and we see an interesting and likely inefficient line. The Cardinals are field goal home dogs to the Detroit Lions this week. Arizona is +0.35 in net EPA despite having played the fifth-most-improved team, Buffalo. Meanwhile, Detroit has regressed.

This week’s Lions-Cardinals game sets up as a Pros-versus-Joes spot. The trend-loving public will want exposure to Dan Campbell’s Lions, who went 5-0 ATS after a loss last season and were a dominant 5-1 ATS as road favorites.

Meanwhile, EPA-trusting sharps have every reason to believe in the Cardinals and little reason to believe in the Lions. Arizona’s ing offense is +0.53 EPA per dropback YoY. Detroit’s ing defense is +0.05 YoY (so, marginally worse — , we look for negative numbers on defense).

So far, Detroit’s primary source of regression has been in the ing game, with the ing offense down by -0.26 EPA per dropback YoY. The rushing offense has picked things up (0.23; +0.24 YoY), but it’s hard to blow teams out by keeping the ball on the ground.

While I do like Arizona +3, and I may end up with some additional exposure to that line by kickoff, I’m opening my week of NFL betting with an NFC West teaser: Give me Arizona +8.5 and Seattle +2.5 for -116 at DraftKings. The same bet will cost you upwards of -130 everywhere else.

Sign up for The Profit Isaiah for all my picks every day! All my results are tracked here. Take 50% off your first two months with code “TPI50”.

NFL Expert Pick for Week 3: Arizona +8.5/Seattle +2.5 -116 at DraftKings

Categories NFL
DraftKings Pick6 Predictions for NFL Week 3 TNF: Patriots-Jets
South Alabama-Appalachian State Odds, Expert Pick & Prediction (Sept. 19)
Isaiah Sirois

Author

Isaiah Sirois

Isaiah Sirois is a sports betting analyst at OddsShopper specializing in basketball, football and motorsports. Basketball is Isaiah’s favorite sport to handicap, and he has covered NBA, WNBA, NCAA and FIBA markets for OddsShopper and other sites. However, Isaiah’s favorite sport to follow is auto racing, and you can usually find him watching NASCAR or IndyCar on Sundays. He will be a fan of Team Penske and Ford Performance until the end of time. Isaiah graduated with a bachelor’s degree in history from Emory University and briefly attended Vanderbilt Law School before dropping out to work at OddsShopper.

Next Story

Why the Sportsbooks Hate You When You Actually Start Winning

Trending & Related

DraftKings Pick6 Predictions for the Super Bowl

Super Bowl Best Bets: Lindy’s NFL Leans, Likes & Locks

Super Bowl Anytime Touchdown Scorers: Best Bets for Super Bowl LIX

Betting 101

Why the Sportsbooks Hate You When You Actually Start Winning

What is Portfolio EV? Guide to +EV Sports Betting

Sports Betting Software Showdown: Which Tool Is Right for You?

3 Betting Mistakes That Portfolio EV Catches Instantly (And How It Fixes Them)

Sports Betting Resources

  • Positive EV NFL Bets
  • Expert NFL Picks
  • Live NBA Odds
  • Positive EV NBA Bets
  • Expert NBA Picks
  • Live NFL Odds
  • NFL Parlay Calculator
  • Positive EV MLB Bets
  • Expert MLB Picks
  • Positive EV College Football Bets
  • Expert College Football Picks

Featured Articles

Why the Sportsbooks Hate You When You Actually Start Winning
May 20, 2025 2:17 pm | Dave Loughran
What is Dinger Tuesday? How to Beat FanDuel’s Promotion
May 20, 2025 2:10 pm | Isaiah Sirois
Get a 7-DAY FREE TRIAL Of Portfolio EV Today!
May 20, 2025 10:12 am | Sam Smith
How Portfolio EV Built My NBA Bankroll from $100 to $1,200
May 16, 2025 7:11 am | Greg Ehrenberg
You Don’t Need to Be a Genius to Beat the Books — Just the Right Tools
April 26, 2025 8:15 am | Dave Loughran
NBA Playoffs Are Heating Up — And Portfolio EV s Are Cashing In
April 22, 2025 3:02 pm | Sam Smith

Related Articles

DraftKings Pick6 Predictions for the Super Bowl
February 9, 2025 10:26 am | Danny Burke
Super Bowl Best Bets: Lindy’s NFL Leans, Likes & Locks
February 9, 2025 7:55 am | Eric Lindquist
How to Bet on the Super Bowl Like a Pro
February 9, 2025 7:53 am | Sam Smith
Super Bowl Anytime Touchdown Scorers: Best Bets for Super Bowl LIX
February 9, 2025 7:41 am | Danny Burke
DraftKings Pick6 Predictions for the NFL Conference Championship
January 26, 2025 1:16 pm | Danny Burke
FREE Conference Championship Sunday NFL Pick Today: Ben’s Sharp Bet of the Day (January 26)
January 26, 2025 9:59 am | Ben Rasa

PrizePicks, DraftKings Pick6 & Underdog Cheat Sheet: Best More/Less Picks Today for NBA & MLB (May 23)
May 23, 2025 11:05 am
Sports Betting Without Knowing the Sport: How Market-Based +EV Betting Can Beat the Books
May 22, 2025 2:37 pm
Underdog Fantasy Pick’em Predictions Today: Anthony Edwards (May 22)
May 22, 2025 1:07 pm
Best ParlayPlay Promo Code Today
May 22, 2025 6:57 am
Best Sleeper Promo Code Today
May 22, 2025 6:56 am
Best Underdog Promo Code Today
May 22, 2025 6:56 am
Best Vivid Picks Promo Code Today
May 22, 2025 6:56 am
The Portfolio EV Lab Just Got a Massive Data Upgrade
May 20, 2025 2:47 pm
Why the Sportsbooks Hate You When You Actually Start Winning
May 20, 2025 2:17 pm
What is Dinger Tuesday? How to Beat FanDuel’s Promotion
May 20, 2025 2:10 pm

How Can I Find the Best Sports Betting and DFS App Bonuses?

If you're a new sports bettor, it's hard to know where to start. In fact, it's simpler than it seems, because there are use OddsShopper's Free Bet Converter to maximize your beginning bankroll

Get a bonus code for BetMGM

Get a promo code Caesars Sportsbook

Best DraftKings Promo Code

Get a promo code for DraftKings

Use a promo code for FanDuel

Claim a promo code for PrizePicks

Get a promo code for UnderDog

the ranks of the OddsShopper Hall of Fame

  • Free Expert Picks

    • Free NBA Picks
    • Free MLB Picks
    • Free NFL Picks
    • Free NHL Picks
    • Free NCAAB Picks
    • Free NCAAF Picks
    • Free Golf Picks
    • Free UFC Picks
    • Free EPL Picks
    • Free Tennis Picks
    • Free WNBA Picks
  • Positive EV Bets

    • Positive EV NBA Bets
    • Positive EV MLB Bets
    • Positive EV NFL Bets
    • Positive EV NHL Bets
    • Positive EV NCAAB Bets
    • Positive EV NCAAF Bets
    • Positive EV Golf Bets
    • Positive EV UFC Bets
    • Positive EV EPL Bets
    • Positive EV Tennis Bets
    • Positive EV WNBA Bets
  • Betting Tools

    • Arbitrage Opportunities
    • Parlay Builder
    • PrizePicks Entry Builder
    • Underdog Entry Builder
    • Sleeper Entry Builder
    • Free Bet Converter
  • Articles

    • All Articles
    • NBA Articles
    • NFL Articles
    • NCAAF Articles
    • MLB Articles
    • PGA Articles
    • NHL Articles
    • NASCAR Articles
    • MMA Articles
  • Betting Calculators

    • Expected Value Calculator
    • Hold Calculator
    • Parlay Calculator
    • Odds Converter
  • Live Odds

    • Live NBA Odds
    • Live MLB Odds
    • Live NFL Odds
    • Live NHL Odds
    • Live NCAAB Odds
    • Live NCAAF Odds
    • Live Golf Odds
    • Live UFC Odds
    • Live EPL Odds
    • Live Tennis Odds
  • Sportsbook Promo Codes

    • BetMGM Bonus Codes
    • Bet365 Bonus Codes
    • FanDuel Promo Codes
    • DraftKings Promo Codes
    • Caesars Promo Codes
    • BetRivers Promo Codes
    • Sleeper Fantasy Promo Codes
    • Underdog Fantasy Promo Codes
    • Betr Picks Promo Codes

    • Us
    • of Use
    • Stokastic
OddsShopper Logo
© 2024 Stokastic.All Rights reserved.
This site contains commercial content, We may be compensated for the links provided on this page. The content on this page is for informational purposes only. OddsShopper makes no representation or warranty as to the accuracy of the information given or the outcome of any game or event. Please play responsibly. Only customers 21 and over are permitted to play. If you or someone you know has a gambling problem and wants help, call 1-800-GAMBLER.