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49ers-Rams Odds, Moneyline and Trends – Sunday, September 17, 2023

Updated September 17, 2023 | 7:31 am CDT by OddsShopper Staff

In this post, we’ll be looking at the 49ers-Rams odds, moneyline and trends for the Sunday matchup. The San Francisco 49ers will be on the road Sunday afternoon to take on the Los Angeles Rams. The Los Angeles Rams come into Sunday as the underdog, with San Francisco 49ers favored to win. The game is set to kickoff at 9/17/2023 4:05 PM ET. Nonetheless, onto our 49ers-Rams odds, trends, and moneyline for today’s game. React App

49ers – Rams Odds

49ers – Rams odds provided by PointsBet
Team Moneyline Spread O/U
Los Angeles Rams +260 +7.5, -110 Over 45.5, -110
San Francisco 49ers -350 -7.5, -110 Under 45.5, -110

The San Francisco 49ers are favored in this matchup with -350 odds for the moneyline and -110 odds for the -7.5 spread on PointsBet. The Los Angeles Rams are +7.5 point underdogs, with -110 odds and +260 odds for the moneyline in this matchup vs the San Francisco 49ers.

Moneyline Odds

Bet Side Bet365 BetMGM BetRivers Caesars DraftKings FanDuel PointsBet SugarHouse SuperBook Tipico Unibet WynnBET
Los Angeles Rams +290 +290 +290 +285 +275 +320 +260 +290 +290 +290 +290 +295
San Francisco 49ers -370 -375 -345 -365 -345 -405 -350 -345 -380 N/A -345 -360

Moneyline Trends

  • In the last 3 of 3 Home games, the San Francisco 49ers have hit the Moneyline bet (ROI: 42.8%)
  • The San Francisco 49ers have not hit the Moneyline in 2 of their last 3 Away games (ROI: -59.3%)
  • The San Francisco 49ers have not hit the Moneyline in 2 of their last 6 games (ROI: -8.2%)
  • The Los Angeles Rams have not hit the Moneyline in 3 of their last 3 Away games (ROI: -100.0%)
  • The Los Angeles Rams have not hit the Moneyline in 3 of their last 4 games (ROI: -70.2%)

Point Spread Odds

Bet Side Bet365 BetMGM BetRivers Caesars DraftKings FanDuel PointsBet SugarHouse SuperBook Tipico Unibet WynnBET
Los Angeles Rams +8.0, -110 +9.0, -120 +3.5, +165 +8.0, -115 +13.5, -209 -5.5, +600 +7.5, -110 -2.0, +290 +8.0, -110 +13.0, -208 +8.5, -118 +7.5, -110
San Francisco 49ers -8.0, -110 -9.0, +100 -4.5, -186 -8.0, -105 -10, +112 N/A -7.5, -110 +2.0, -480 -8.0, -110 N/A -8.5, -104 -7.5, -110

Point Spread Trends

  • The San Francisco 49ers have covered the Point Spread in 3 of their last 3 Home games (ROI: 90.9%)
  • The San Francisco 49ers have not covered the Point Spread in 2 of their last 3 Away games (ROI: -35.8%)
  • The San Francisco 49ers have hit the Point Spread in 4 of their last 6 games (ROI: 27.6%)
  • In the last 3 of 3 Away games, the Los Angeles Rams have not hit the Point Spread bet (ROI: -100.0%)
  • The Los Angeles Rams have not covered the Point Spread in 4 of their last 4 games (ROI: -100.0%)

Total Odds

Bet Side BetMGM BetRivers Caesars DraftKings FanDuel PointsBet SugarHouse SuperBook Tipico Unibet WynnBET
Over 42.5, -155 55.0, +300 44.5, -110 52.0, +206 57.5, +420 45.5, -110 51.5, +195 44.5, -110 44.5, -116 44.5, -117 45.0, -110
Under 42.5, +120 48.0, -167 44.5, -110 54.0, -369 17.5, +5500 45.5, -110 37.0, +250 44.5, -110 44.5, -104 44.5, -105 45.0, -110

Our 49ers – Rams Prediction:

Los Angeles Rams Moneyline at FanDuel

Best San Francisco 49ers-Los Angeles Rams Player Props

Bet Odds Sportsbook
Brock Purdy – Total ing Yards – Under 216.5 +110 DraftKings
Jauan Jennings – Total Receiving Yards – Over 14.5 -110 Bet365
Christian McCaffrey – Total Rushing Yards – Under 66.5 -105 DraftKings
Brandon Aiyuk – Longest Reception – Under 23.5 -115 Caesars
Kyle Juszczyk – Last Touchdown Scorer – Kyle Juszczyk +6000 FanDuel

Player Prop Trends

  • In the last 1 of 5 games, Anytime Touchdown Scorer bet (ROI: 85.0%)
  • In the last 5 of 5 games, Anytime Touchdown Scorer bet (ROI: -100.0%)
  • In the last 1 of 5 games, Anytime Touchdown Scorer bet (ROI: -20.0%)
  • In the last 1 of 5 games, Anytime Touchdown Scorer bet (ROI: 81.6%)
  • In the last 3 of 5 games, Anytime Touchdown Scorer bet (ROI: -60.0%)

Looking for an edge on this NFL matchup featuring the San Francisco 49ers vs Los Angeles Rams?

Check out OddsShopper’s odds tools to sort and filter through the best bets on NFL odds now. Additionally, check out the sharp sportsbook projection system to gain the best edge. Check out our NFL compare tool to see which book is offering the best odds!

Check out our Other NFL Week 2 predictions and picks!

Don’t forget about our Expert Week 2 NFL Picks post.

Nonetheless, hopefully you found this 49ers-Rams Odds, Moneyline and Trends post helpful.

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